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VK-2019

Chemical Structure : VK-2019

CAS No.: 2044520-06-9

VK-2019 (VK2019)

Catalog No.: PC-23857Not For Human Use, Lab Use Only.

VK-2019 is a selective small molecule inhibitor of Epstein-Barr virus Nuclear Antigen 1 (EBNA1), reduces EBV genome copy number and viral gene expression in EBV-positive nasopharyngeal carcinoma.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

VK-2019 is a selective small molecule inhibitor of Epstein-Barr virus Nuclear Antigen 1 (EBNA1), reduces EBV genome copy number and viral gene expression in EBV-positive nasopharyngeal carcinoma.

Physicochemical Properties

M.Wt 451.52
Formula C29H25NO4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(1H-Indol-6-yl)-3-((4-(((tetrahydro-2H-pyran-4-yl)oxy)methyl)phenyl)ethynyl)benzoic acid

References

1. Davis MT, et al. Biomed Chromatogr. 2024 Feb;38(2):e5775.

2. Colevas AD, et al. Clin Cancer Res. 2025 Jan 20. doi: 10.1158/1078-0432.CCR-24-2814.

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