PXS-5129A |CAS:2125955-76-0 Probechem Biochemicals

Chemical Structure : PXS-5129A

PXS-5129A (PXS5129A)

Catalog No.: PC-38098Not For Human Use, Lab Use Only.

PXS-5129A is the pro-drug form of PXS-5120A, a potent, selective, irreversible inhibitor of Lysyl oxidase-like 2 (LOXL2).

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Biological Activity

PXS-5129A is the pro-drug form of PXS-5120A, a potent, selective, irreversible inhibitor of Lysyl oxidase-like 2 (LOXL2).
PXS-5129A displays anti-fibrotic activity in models of liver and lung fibrosis.

Physicochemical Properties

M.Wt	510.021
Formula	C24H29ClFN3O4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(Z)-ethyl 1-(4-amino-2-fluorobut-2-en-1-yl)-3-(3-(N,N-dimethylsulfamoyl)phenyl)-2-methyl-1H-indole-5-carboxylate hydrochloride

References

1. Findlay AD, et al. J Med Chem. 2019 Nov 14;62(21):9874-9889.

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PXS-5129A (PXS5129A)

Biological Activity

Physicochemical Properties

References

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