eCIRP/TREM-1 inhibitor M3 | Probechem Biochemicals

Chemical Structure : eCIRP/TREM-1 inhibitor M3

eCIRP/TREM-1 inhibitor M3 (eCIRP-derived peptide (RGFFRGG))

Catalog No.: PC-38147Not For Human Use, Lab Use Only.

eCIRP/TREM-1 inhibitor M3 (RGFFRGG) is a small CIRP-derived peptide that inhibits the eCIRP/TREM-1 interaction.

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Biological Activity

eCIRP/TREM-1 inhibitor M3 (RGFFRGG) is a small CIRP-derived peptide that inhibits the eCIRP/TREM-1 interaction.
M3 decreases systemic, pulmonary, and cardiac inflammation, improves cardiac dysfunction, and increases survival in a murine model of neonatal sepsis.

Physicochemical Properties

M.Wt	795.90
Formula	C36H53N13O8
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	L-arginylglycyl-L-phenylalanyl-L-phenylalanyl-L-arginylglycylglycine

References

1. Naomi-Liza Denning, et al. Mol Med. 2020 Dec 4;26(1):121.

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eCIRP/TREM-1 inhibitor M3 (eCIRP-derived peptide (RGFFRGG))

Biological Activity

Physicochemical Properties

References

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