SLC6A19 inhibitor 39 |CAS:2755929-52-1 Probechem Biochemicals

Chemical Structure : SLC6A19 inhibitor 39

CAS No.: 2755929-52-1

SLC6A19 inhibitor 39

Catalog No.: PC-38115Not For Human Use, Lab Use Only.

SLC6A19 inhibitor 39 is a potent, selective and orally efficacious inhibitor of neutral amino acid transporter B0AT1 (SLC6A19) with IC50 of 35 nM.

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2 mg	$278	In stock
5 mg	$458	In stock
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Biological Activity

SLC6A19 inhibitor 39 is a potent, selective and orally efficacious inhibitor of neutral amino acid transporter B0AT1 (SLC6A19) with IC50 of 35 nM.
SLC6A19 inhibitor 39 exhibits excellent pharmacokinetic profile (%F: 66) in mice and efficacious in vivo in diet induced obese (DIO) mice model.

Physicochemical Properties

M.Wt	493.419
Formula	C19H12F5NO5S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-[2-(3,5-Difluorophenoxy)-4-[(trifluoromethyl)sulfonyl]phenyl]benzenesulfonamide

References

1. Jigar Desai, et al. Bioorg Med Chem Lett. 2021 Dec 1;53:128421.

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