Chemical Structure : Larazotide acetate
CAS No.:
881851-50-9
Larazotide acetate
(AT1001, INN-202, GGVLVQPG acetate)
Catalog No. : PC-49429Not For Human Use, Lab Use Only.
Larazotide acetate (AT1001) is a synthetic, competitive octapeptide inhibitor of zonulin, acts as a tight junction regulator to restore intestinal barrier function.
Packing Price Stock Quantity 5 mg $88 In stock 0 1 2 3 4 5 10 mg $128 In stock 0 1 2 3 4 5 25 mg $218 In stock 0 1 2 3 4 5 50 mg $358 In stock 0 1 2 3 4 5 100 mg Get quote 0 1 2 3 4 5
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4942901
Biological Activity
Larazotide acetate (AT1001) is a synthetic, competitive octapeptide inhibitor of zonulin , acts as a tight junction regulator to restore intestinal barrier function.
Physicochemical Properties
M.Wt
785.89
Formula
C34H59N9O12
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
Glycine, glycylglycyl-L-valyl-L-leucyl-L-valyl-L-glutaminyl-L-prolyl-, acetate (1:1)
References
1. Tajik N, et al. Nat Commun. 2020 Apr 24;11(1):1995.
2. Benjamin ER, et al. Mol Ther. 2012 Apr;20(4):717-26.
3. Di Micco S, et al. Int J Mol Sci. 2021 Aug 30;22(17):9427.
4. M C Arrieta, et al. Gut. 2009 Jan;58(1):41-8.
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