SEN177 | Glutaminyl cyclase inhibitor | Probechem Biochemicals

Chemical Structure : SEN177

CAS No.: 2117405-13-5

SEN177 (SEN-177)

Catalog No.: PC-49527Not For Human Use, Lab Use Only.

SEN177 (SEN-177) is a highly potent human glutaminyl cyclase (hQC) inhibitor Ki value of 20 nM.

Packing	Price	Stock
5 mg	$88	In stock
10 mg	$128	In stock
25 mg	$218	In stock
50 mg	$348	In stock
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Biological Activity

SEN177 (SEN-177) is a highly potent human glutaminyl cyclase (hQC) inhibitor Ki value of 20 nM.
SEN177 demonstrated relevant pharmacological properties in in vivo models of Huntington's disease.

Physicochemical Properties

M.Wt	338.390
Formula	C18H19FN6
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	6'-fluoro-2-(4-(4-methyl-4H-1,2,4-triazol-3-yl)piperidin-1-yl)-3,3'-bipyridine

References

1. Pozzi C, et al. J Biol Inorg Chem. 2018 Dec;23(8):1219-1226.

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SEN177 (SEN-177)

Biological Activity

Physicochemical Properties

References

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