Chemical Structure : SEN177
CAS No.: 2117405-13-5
Catalog No.: PC-49527Not For Human Use, Lab Use Only.
SEN177 (SEN-177) is a highly potent human glutaminyl cyclase (hQC) inhibitor Ki value of 20 nM.
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SEN177 (SEN-177) is a highly potent human glutaminyl cyclase (hQC) inhibitor Ki value of 20 nM.
SEN177 demonstrated relevant pharmacological properties in in vivo models of Huntington's disease.
M.Wt | 338.390 | |
Formula | C18H19FN6 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
6'-fluoro-2-(4-(4-methyl-4H-1,2,4-triazol-3-yl)piperidin-1-yl)-3,3'-bipyridine |
1. Pozzi C, et al. J Biol Inorg Chem. 2018 Dec;23(8):1219-1226.
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