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SEN177

Chemical Structure : SEN177

CAS No.: 2117405-13-5

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SEN177 (SEN-177)

Catalog No.: PC-49527Not For Human Use, Lab Use Only.

SEN177 (SEN-177) is a highly potent human glutaminyl cyclase (hQC) inhibitor Ki value of 20 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

SEN177 (SEN-177) is a highly potent human glutaminyl cyclase (hQC) inhibitor Ki value of 20 nM.
SEN177 demonstrated relevant pharmacological properties in in vivo models of Huntington's disease.

Physicochemical Properties

M.Wt 338.390
Formula C18H19FN6
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

6'-fluoro-2-(4-(4-methyl-4H-1,2,4-triazol-3-yl)piperidin-1-yl)-3,3'-bipyridine

References

1. Pozzi C, et al. J Biol Inorg Chem. 2018 Dec;23(8):1219-1226.

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