Sepin-1 |CAS:163126-81-6 Probechem Biochemicals

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Chemical Structure : Sepin-1

Sepin-1 (Sepin1)

Catalog No.: PC-62753Not For Human Use, Lab Use Only.

Sepin-1 is a small molecule, noncompetitive separase inhibitor with IC50 of 14.8 uM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Sepin-1 is a small molecule, noncompetitive separase inhibitor with IC50 of 14.8 uM; inhibits the growth of human cancer cell lines and breast cancer xenograft tumors in mice by inhibiting cell proliferation and inducing apoptosis.

Physicochemical Properties

M.Wt	223.188
Formula	C9H9N3O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2,2-dimethyl-5-nitro-2H-benzo[d]imidazole 1,3-dioxide

References

1. Do HT, et al. Bioorg Med Chem Lett. 2016 Sep 15;26(18):4446-50.

2. Zhang N, et al. J Biomol Screen. 2014 Jul;19(6):878-89.

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Sepin-1 (Sepin1)

Biological Activity

Physicochemical Properties

References

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