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RBPI-4

Chemical Structure : RBPI-4

CAS No.: 1355339-07-9

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RBPI-4 (RBPI4)

Catalog No.: PC-62413Not For Human Use, Lab Use Only.

RBPI-4 is a selective small molecule inhibitor of poly(ADP-ribose) glycohydrolase (PARG) with IC50 of 3.0 uM, effectively inhibit PARG in cellular lysate.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

RBPI-4 is a selective small molecule inhibitor of poly(ADP-ribose) glycohydrolase (PARG) with IC50 of 3.0 uM, effectively inhibit PARG in cellular lysate.

Physicochemical Properties

M.Wt 555.817
Formula C21H13BrClFN2O4S2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(Z)-3-(5-(5-bromo-1-(2-chloro-6-fluorobenzyl)-2-oxoindolin-3-ylidene)-4-oxo-2-thioxothiazolidin-3-yl)propanoic acid

References

1. Finch KE, et al. ACS Chem Biol. 2012 Mar 16;7(3):563-70.

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