Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : TLK1 inhibitor J54
CAS No.: 4734-59-2
Catalog No.: PC-38651Not For Human Use, Lab Use Only.
TLK1 inhibitor J54 (J3-54) is a potent, small-molecule TLK1 inhibitor, induces apoptosis in AS PCa cells, suppresses growth of LNCaP xenografts combined with bicalutamide.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $128 | In stock | |
| 10 mg | $188 | In stock | |
| 25 mg | $328 | In stock | |
| 50 mg | $528 | In stock | |
| 100 mg | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
TLK1 inhibitor J54 (J3-54) is a potent, small-molecule TLK1 inhibitor, induces apoptosis in AS PCa cells, suppresses growth of LNCaP xenografts combined with bicalutamide.
J54 showed much weaker binding to the DR2 than THD or risperidone.
J54 exhibits TLK1 inhibition with reduced pAKT S473 levels in a dose-dependent manner.
| M.Wt | 312.431 | |
| Formula | C18H20N2OS | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
4-(2-(10H-phenothiazin-10-yl)ethyl)morpholine |
|
1. Vibha Singh, et al. iScience. 2020 Aug 20;23(9):101474.
2. Md Imtiaz Khalil, et al. Pathophysiology. 2021 Sep; 28(3): 339–354.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
