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CBK034026C

Chemical Structure : CBK034026C

CAS No.:

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CBK034026C (CBK 034026C)

Catalog No.: PC-49150Not For Human Use, Lab Use Only.

CBK034026C is a small molecule targeting metabolic vulnerabilities caused by N-acetyltransferase 2 (NAT2) activity, exhibits specific toxicity towards colorectal cancer (CRC) cells with high NAT2 activity.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    CBK034026C is a small molecule targeting metabolic vulnerabilities caused by N-acetyltransferase 2 (NAT2) activity, exhibits specific toxicity towards colorectal cancer (CRC) cells with high NAT2 activity.
    CBK034026C activated the Nf-kB pathway, which is similar to ouabain, a potent inhibitor of the Na+/K+-ATPase.

    Physicochemical Properties

    M.Wt 468.583
    Formula C23H31F3N4OS
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    5-(((1-butylpiperidin-4-yl)methyl)amino)-N-cyclobutyl-7-(trifluoromethyl)thieno[3,2-b]pyridine-3-carboxamide

    References

    1. Xiaonan Zhang, et al. Biochem Pharmacol. 2022 Jul 21;115184.

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