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Chemical Structure : NPD389
Catalog No.: PC-49093Not For Human Use, Lab Use Only.
NPD389 is a potent, selective, fast-binding uncompetitive inhibitor of NADP+-dependent malic enzyme 2 (ME2) with IC50 of 4.63 uM, NPD389 is a mixed-type competitive inhibitor for the substrate L-malate and an uncompetitive inhibitor for the other substrate NAD+.
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NPD389 is a potent, selective, fast-binding uncompetitive inhibitor of NADP+-dependent malic enzyme 2 (ME2) with IC50 of 4.63 uM, NPD389 is a mixed-type competitive inhibitor for the substrate L-malate and an uncompetitive inhibitor for the other substrate NAD+.
| M.Wt | 352.342 | |
| Formula | C20H16O6 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Yi Wen, et al. Acta Pharmacol Sin. 2014 May;35(5):674-84.
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