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STL427944

Chemical Structure : STL427944

CAS No.: 292028-62-7

STL427944 (STL 427944)

Catalog No.: PC-22338Not For Human Use, Lab Use Only.

STL427944 is a small molecule inhibitor of forkhead box protein M1 (FOXM1), selectively suppresses FOXM1 by inducing the relocalization of nuclear FOXM1 protein to the cytoplasm and promoting its subsequent degradation by autophagosomes.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

STL427944 is a small molecule inhibitor of forkhead box protein M1 (FOXM1), selectively suppresses FOXM1 by inducing the relocalization of nuclear FOXM1 protein to the cytoplasm and promoting its subsequent degradation by autophagosomes.

Physicochemical Properties

M.Wt 485.50
Formula C25H23N7O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(E)-3-((2-(4-morpholino-6-(phenylamino)-1,3,5-triazin-2-yl)hydrazineylidene)methyl)phenyl furan-2-carboxylate

References

1. Chesnokov MS, et al. Cell Death Dis. 2021 Jul 14;12(7):704.

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