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STL427944

Chemical Structure : STL427944

CAS No.: 292028-62-7

STL427944 (STL 427944)

Catalog No.: PC-22338Not For Human Use, Lab Use Only.

STL427944 is a small molecule inhibitor of forkhead box protein M1 (FOXM1), selectively suppresses FOXM1 by inducing the relocalization of nuclear FOXM1 protein to the cytoplasm and promoting its subsequent degradation by autophagosomes.

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    Biological Activity

    STL427944 is a small molecule inhibitor of forkhead box protein M1 (FOXM1), selectively suppresses FOXM1 by inducing the relocalization of nuclear FOXM1 protein to the cytoplasm and promoting its subsequent degradation by autophagosomes.

    Physicochemical Properties

    M.Wt 485.50
    Formula C25H23N7O4
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (E)-3-((2-(4-morpholino-6-(phenylamino)-1,3,5-triazin-2-yl)hydrazineylidene)methyl)phenyl furan-2-carboxylate

    References

    1. Chesnokov MS, et al. Cell Death Dis. 2021 Jul 14;12(7):704.

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