JNJ-DHODH-IN-19

Chemical Structure : JNJ-DHODH-IN-19

Catalog No.: PC-49782Not For Human Use, Lab Use Only.

JNJ-DHODH-IN-19 is a potent, selective DHODH inhibitor with IC50 of 1.1 nM, inhibits MOLM-13 cell proliferation with IC50 of 2.0 nM.

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Biological Activity

JNJ-DHODH-IN-19 is a potent, selective DHODH inhibitor with IC50 of 1.1 nM, inhibits MOLM-13 cell proliferation with IC50 of 2.0 nM.

M.Wt	518.85
Formula	C20H19ClF4N6O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-N-(2-chloro-4-methylpyridin-3-yl)-6-(4-ethyl-3-(hydroxymethyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)-5-fluoro-2-((1,1,1-trifluoropropan-2-yl)oxy)nicotinamide

1. Justin S Cisar, et al. J Med Chem. 2022 Aug 25;65(16):11241-11256.