AE1 inhibitor 22

Chemical Structure : AE1 inhibitor 22

Catalog No.: PC-21411Not For Human Use, Lab Use Only.

AE1 inhibitor 22 is a small molecule inhibitor of the anion exchanger 1 transporter (AE1) with IC50 of 18 uM.

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Biological Activity

AE1 inhibitor 22 is a small molecule inhibitor of the anion exchanger 1 transporter (AE1) with IC50 of 18 uM.
Anion exchanger 1 (AE1), a member of the solute carrier (SLC) family, is the primary bicarbonate transporter in erythrocytes, regulating pH levels and CO2 transport between lungs and tissues.

Physicochemical Properties

M.Wt	429.46
Formula	C19H22F3N3O3S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-ethyl-5-(3-(3-(3-(trifluoromethyl)phenyl)propyl)ureido)benzenesulfonamide

References

1. Capper MJ, et al. Nat Struct Mol Biol. 2023 Sep 7. doi: 10.1038/s41594-023-01085-6.

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AE1 inhibitor 22

Biological Activity

Physicochemical Properties

References

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