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Heparanase-1 inhibitor 18

Chemical Structure : Heparanase-1 inhibitor 18

CAS No.: 2876926-27-9

Heparanase-1 inhibitor 18

Catalog No.: PC-21360Not For Human Use, Lab Use Only.

Heparanase-1 inhibitor 18 is a potent, selective inhibitor of heparanase-1 (HPSE1) with IC50 of 442 nM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Heparanase-1 inhibitor 18 is a potent, selective inhibitor of heparanase-1 (HPSE1) with IC50 of 442 nM.

Physicochemical Properties

M.Wt 424.45
Formula C23H24N2O6
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(5S,6R,7R,8S)-7,8-dihydroxy-6-methoxy-2-[2-(3-phenoxyphenyl)ethyl]-5,6,7,8-tetrahydroimidazo[1,2-a]pyridine-5-carboxylic acid

References

1. Imai Y, et al. Bioorg Med Chem. 2023 Oct 1;93:117460.

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