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Chemical Structure : trans-AUCB
CAS No.: 885012-33-9
Catalog No.: PC-60090Not For Human Use, Lab Use Only.
trans-AUCB is a potent, specific and orally bioavailable soluble epoxide hydrolase (sEH) inhibitor with IC50 of 1.3 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $98 | In stock | |
| 10 mg | $148 | In stock | |
| 25 mg | $278 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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trans-AUCB is a potent, specific and orally bioavailable soluble epoxide hydrolase (sEH) inhibitor with IC50 of 1.3 nM.
trans-AUCB shows potential in vivo to treat hypotension in lipopolysaccharide challenged murine models.
trans-AUCB prevents the pericyte loss and vascular permeability in animal model of diabetic retinopathy.
| M.Wt | 412.5 | |
| Formula | C24H32N2O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
trans-4-[4-(3-adamantan-1-ylureido)cyclohexyloxy]benzoic acid |
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1. Hwang SH, et al. J Med Chem. 2007 Aug 9;50(16):3825-40.
2. Hwang SH, et al. J Med Chem. 2011 Apr 28;54(8):3037-50.
3. Hu J, et al. Nature. 2017 Dec 14;552(7684):248-252.
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