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Chemical Structure : CK-2127107
CAS No.: 1345410-31-2
Catalog No.: PC-60222Not For Human Use, Lab Use Only.
CK-2127107 (CK-107, Reldesemtiv) is a novel orally active fast skeletal troponin activator, selectively activates fast skeletal myofibrils with EC50 of 3.4 uM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $298 | In stock | |
| 10 mg | $458 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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CK-2127107 (CK-107, Reldesemtiv) is a novel orally active fast skeletal troponin activator, selectively activates fast skeletal myofibrils with EC50 of 3.4 uM.
CK-2127107 (CK-107, Reldesemtiv) has no effect on slow skeletal or cardiac myofibrils.
CK-2127107 (CK-107, Reldesemtiv) significantly improves rotarod performance in exercise-intolerant LAD-HF rats.
| M.Wt | 384.391 | |
| Formula | C19H18F2N6O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
1-[2-({[trans-3-fluoro-1-(3-fluoropyridin-2-yl)cyclobutyl]methyl}amino)pyrimidin-5-yl]-1H-pyrrole-3-carboxamide |
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1. Hwee DT, et al. J Pharmacol Exp Ther. 2015 Apr;353(1):159-68.
2. Calder AN, et al. J Med Chem. 2016 Nov 23;59(22):10067-10083.
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