Chemical Structure : Shield-1
CAS No.:
914805-33-7
Shield-1
(Shld-1;Shield 1;Shield 1)
Catalog No. : PC-60184Not For Human Use, Lab Use Only.
Shield-1 is a cell-permeable FKBP ligand that is designed to protect an otherwise unstable protein domain from degradation.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-6018401
Biological Activity
Shield-1 is a cell-permeable FKBP ligand that is designed to protect an otherwise unstable protein domain from degradation.
Physicochemical Properties
M.Wt
748.9
Formula
C42H56N2O10
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
(S)-(R)-3-(3,4-Dimethoxyphenyl)-1-(3-(2-morpholinoethoxy)phenyl) propyl 1-((S)-2-(3,4,5-trimethoxyphenyl)butanoyl)piperidine-2-carboxylate
References
1. Banaszynski, et al. Cell.
2. Rodriguez S, et al. Chem Biol.
3. Bonger KM, et al. Nat Chem Biol.
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