Des 1 inhibitor GT11 | Des1 inhibitor | Probechem Biochemicals

Chemical Structure : Des 1 inhibitor GT11

Des 1 inhibitor GT11 ((1R,2S)-Deoxy-PR280)

Catalog No.: PC-26798Not For Human Use, Lab Use Only.

Des 1 inhibitor GT11 ((1R,2S)-Deoxy-PR280) is a competitive inhibitor of dihydroceramide desaturase with Ki of 6 uM, induces Des1 inhibition in rat liver microsomes with IC50 of 20 uM.

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Biological Activity

Des 1 inhibitor GT11 ((1R,2S)-Deoxy-PR280) is a competitive inhibitor of dihydroceramide desaturase with Ki of 6 uM, induces Des1 inhibition in rat liver microsomes with IC50 of 20 uM.

Physicochemical Properties

M.Wt	437.71
Formula	C27H51NO3
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-((1R,2S)-1,3-dihydroxy-1-(2-tridecylcycloprop-1-en-1-yl)propan-2-yl)octanamide

References

1. G. Triola, et al. Mol. Pharmacol., 66 (2004), pp. 1671-1678.

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Des 1 inhibitor GT11 ((1R,2S)-Deoxy-PR280)

Biological Activity

Physicochemical Properties

References

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