PR280 | Des1 inhibitor | Probechem Biochemicals

Chemical Structure : PR280

Catalog No.: PC-26797Not For Human Use, Lab Use Only.

PR280 is a potent small molecule inhibitor of dihydroceramide desaturase 1 (Des1) with IC50 of 700 nM.

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Biological Activity

PR280 is a potent small molecule inhibitor of dihydroceramide desaturase 1 (Des1) with IC50 of 700 nM.

M.Wt	451.69
Formula	C27H49NO4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-((1R,2S)-1,3-dihydroxy-1-(3-oxo-2-tridecylcycloprop-1-en-1-yl)propan-2-yl)octanamide

1. Pablo Rivero, et al. Bioorg Chem. 2024 Apr:145:107233.