HMGCS1 inhibitor CNP7

You are here:Home-Chemical Inhibitors & Agonists-Others-Other Targets-HMGCS1 inhibitor CNP7

Chemical Structure : HMGCS1 inhibitor CNP7

Catalog No.: PC-26814Not For Human Use, Lab Use Only.

CNP7 is a potent, selective, covalent HMG-CoA synthase 1 (HMGCS1) inhibitor, reduces HMG-CoA levels and global protein prenylation.

Packing	Price	Stock	Quantity
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

Get Quotation Now

* Please select Quantity before adding items.

or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

CNP7 is a potent, selective, covalent HMG-CoA synthase 1 (HMGCS1) inhibitor, reduces HMG-CoA levels and global protein prenylation.
CNP7 engages the catalytic cysteine Cys129 within HMGCS1′s hydrophobic pocket.
CNP7 (5 uM) reduces cellular HMG-CoA levels and global protein prenylation in HCT116 cells.
CNP7 (5 uM) inhibits cell proliferation by disrupting geranylgeranyl pyrophosphate metabolism in HCT116 cells.

Physicochemical Properties

M.Wt	386.46
Formula	C23H22N4O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-1-cyano-N-((3'-(prop-2-yn-1-ylcarbamoyl)-[1,1'-biphenyl]-3-yl)methyl)pyrrolidine-3-carboxamide

References

1. Sun L, et al. J Am Chem Soc. 2026 May 13. doi: 10.1021/jacs.6c02556.

Overnight Delivery
Fast & Safe Delivery Worldwide
Rewards Program

About Us

Our Services

Site Map

Join with Us
Product Use Citations

Pharmacological Glossary Abbreviations

Abbreviations

Quality Manual

Inquiry Form
How to Order

Terms & Conditions

Credit Card Payment

Shipping Rates & Policies

Privacy Policy
sales@probechem.com