Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : LY 2318912
Catalog No.: PC-63017Not For Human Use, Lab Use Only.
LY 2318912 is a potent, competitive, small molecule inhibitor of anandamide uptake with IC50 of 7.27 nM, shows high affinity against anandamide transporter binding site with Kd o f7.62 nM.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
LY 2318912 is a potent, competitive, small molecule inhibitor of anandamide uptake with IC50 of 7.27 nM, shows high affinity against anandamide transporter binding site with Kd o f7.62 nM; elevates anandamide levels 5-fold in the brain and demonstrates efficacy in the formalin paw-licking model of persistent pain with no obvious adverse effects on motor function in rodents.
| M.Wt | 441.193 | |
| Formula | C12H12IN9O2 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. Moore SA, et al. Proc Natl Acad Sci U S A. 2005 Dec 6;102(49):17852-7.
2. Ortar G, et al. Eur J Med Chem. 2008 Jan;43(1):62-72.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
