Welcome to ProbeChem!Global Supplier of Chemical Probes, Inhibitors & Agonists.
    English |     Chinese

Product Inquiry: sales@probechem.com
Order/PO receiving: order@probechem.com

You are here:Home-Chemical Inhibitors & Agonists-Others-Other Targets-HJC0197
HJC0197

Chemical Structure : HJC0197

CAS No.: 1383539-73-8

Add to Favorites

HJC0197 (HJC-0197)

Catalog No.: PC-63108Not For Human Use, Lab Use Only.

HJC0197 is a potent Exchange proteins directly activated by cAMP (EPAC) inhibitor with IC50 of 4.0 uM.

Packing Price Stock Quantity
5 mg $88 In stock
10 mg $138 In stock
25 mg $248 In stock
50 mg $398 In stock
100 mg Get quote
Get Quotation Now
* Please select Quantity before adding items.
 or Bulk Inquiry

Bulk size, bulk discount!

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

HJC0197 is a potent Exchange proteins directly activated by cAMP (EPAC) inhibitor with IC50 of 4.0 uM.
HJC0197 also inhibits EPAC1-mediated Rap1-GDP exchange activity.
HJC0197 does not alter cAMP-induced type I and II PKA holoenzymes activation at 25 uM.

Physicochemical Properties

M.Wt 339.457
Formula C19H21N3OS
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4-cyclopentyl-2-((2,5-dimethylbenzyl)thio)-6-oxo-1,6-dihydropyrimidine-5-carbonitrile

References

1. Chen H, et al. J Med Chem. 2014 May 8;57(9):3651-65.

2. Chen H, et al. Bioorg Med Chem Lett. 2012 Jun 15;22(12):4038-43.

3. Juhász T, et al. Cell Signal. 2014 Mar;26(3):468-82.

Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

Contact Us sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

Get Quote

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • Additional Information: