DKFZ-633 |CAS:2244425-14-5 Probechem Biochemicals

Chemical Structure : DKFZ-633

DKFZ-633 (DKFZ633;DKFZ 633)

Catalog No.: PC-35660Not For Human Use, Lab Use Only.

DKFZ-633 (DKFZ633) is a selective inhibitor of Kallikrein-related peptidase 6 (KLK6) with IC50 of 0.25 uM, demonstrates good selectivity for KLK6 compared to other KLKs.

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Biological Activity

DKFZ-633 (DKFZ633) is a selective inhibitor of Kallikrein-related peptidase 6 (KLK6) with IC50 of 0.25 uM, demonstrates good selectivity for KLK6 compared to other KLKs.
DKFZ-633 is a useful chemical probe to pull down active endogenous KLK6.

Physicochemical Properties

M.Wt	440.503
Formula	C26H24N4O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-((3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)amino)-2-oxoethyl 2-(5-ethynyl-2-methyl-1H-indol-3-yl)acetate

References

1. De Vita E, et al. J Med Chem. 2018 Sep 28. doi: 10.1021/acs.jmedchem.8b01106.

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DKFZ-633 (DKFZ633;DKFZ 633)

Biological Activity

Physicochemical Properties

References

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