OGT inhibitor 4a | O-GlcNAc transferase inhibitor

Chemical Structure : OGT inhibitor 4a

OGT inhibitor 4a (OSMI-4 active form)

Catalog No.: PC-35722Not For Human Use, Lab Use Only.

OGT inhibitor 4a (OSMI-4 active form) is a novel potent, selective O-linked N-acetylglucosamine transferase (OGT) inhibitor with Kd of 8 nM, the active form of OSMI-4.

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Biological Activity

OGT inhibitor 4a (OSMI-4 active form) is a novel potent, selective O-linked N-acetylglucosamine transferase (OGT) inhibitor with Kd of 8 nM, the active form of OSMI-4.

Physicochemical Properties

M.Wt	576.035
Formula	C25H22ClN3O7S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-N-(2-((7-chloro-2-oxo-1,2-dihydroquinoline)-6-sulfonamido)-2-(2-methoxyphenyl)acetyl)-N-(thiophen-2-ylmethyl)glycine

References

1. Martin SES, et al. J Am Chem Soc. 2018 Oct 24;140(42):13542-13545.

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OGT inhibitor 4a (OSMI-4 active form)

Biological Activity

Physicochemical Properties

References

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