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KAN0438241

Chemical Structure : KAN0438241

CAS No.: 1444836-18-3

KAN0438241 (KAN 0438241, KAN-0438241)

Catalog No.: PC-35685Not For Human Use, Lab Use Only.

KAN0438241 (KAN-0438241) is a potent, selective PFKFB3 inhibitor with IC50 of 0.19 uM, 20-fold selectivity over PFKFB4 and no significant inhibition on PFKFB1 and 2.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    KAN0438241 (KAN-0438241) is a potent, selective PFKFB3 inhibitor with IC50 of 0.19 uM, 20-fold selectivity over PFKFB4 and no significant inhibition on PFKFB1 and 2.

    Physicochemical Properties

    M.Wt 403.38
    Formula C19H14FNO6S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    4-((5'-fluoro-2'-hydroxy-[1,1'-biphenyl])-3-sulfonamido)-2-hydroxybenzoic acid

    References

    1. Gustafsson NMS, et al. Nat Commun. 2018 Sep 24;9(1):3872.

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