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HTS13286

Chemical Structure : HTS13286

CAS No.: 727359-12-8

HTS13286 (HTS 13286)

Catalog No.: PC-20302Not For Human Use, Lab Use Only.

HTS13286 is a selective Aquaporin 9 (AQP9) inhibitor with IC50 of 1.5 uM (inhibition of CHO-AQP9 cell water permeability).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    HTS13286 is a selective Aquaporin 9 (AQP9) inhibitor with IC50 of 1.5 uM (inhibition of CHO-AQP9 cell water permeability).
    HTS13286 shows little to no activity against AQP3, AQP7, and AQP8.

    Physicochemical Properties

    M.Wt 415.51
    Formula C16H13N7OS3
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    2-((4-methyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-N-(5-(thiophen-2-yl)-1,3,4-thiadiazol-2-yl)acetamide

    References

    1. Sabina Jelen, et al. J Biol Chem. 2011 Dec 30;286(52):44319-25.

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