Chemical Structure : 2,5-pyridinedicarboxylic acid
CAS No.: 100-26-5
Catalog No.: PC-20213Not For Human Use, Lab Use Only.
2,5-pyridinedicarboxylic acid is a highly selective D-dopachrome tautomerase (D-DT, MIF2) inhibitor with Ki of 17.2 uM, 79-fold selectivity over MIF, effectively blocks the D-DT-induced activation of CD74.
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2,5-pyridinedicarboxylic acid is a highly selective D-dopachrome tautomerase (D-DT, MIF2) inhibitor with Ki of 17.2 uM, 79-fold selectivity over MIF, effectively blocks the D-DT-induced activation of CD74.
M.Wt | 167.12 | |
Formula | C7H5NO4 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
2,5-pyridinedicarboxylic acid |
1. Parkins A, et al. Structure. 2023 Mar 2;31(3):355-367.e4.
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