2,5-pyridinedicarboxylic acid

Chemical Structure : 2,5-pyridinedicarboxylic acid

CAS No.: 100-26-5

Catalog No.: PC-20213Not For Human Use, Lab Use Only.

2,5-pyridinedicarboxylic acid is a highly selective D-dopachrome tautomerase (D-DT, MIF2) inhibitor with Ki of 17.2 uM, 79-fold selectivity over MIF, effectively blocks the D-DT-induced activation of CD74.

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100 mg	$148	In stock
500 mg	$288	In stock
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Biological Activity

2,5-pyridinedicarboxylic acid is a highly selective D-dopachrome tautomerase (D-DT, MIF2) inhibitor with Ki of 17.2 uM, 79-fold selectivity over MIF, effectively blocks the D-DT-induced activation of CD74.

Physicochemical Properties

M.Wt	167.12
Formula	C7H5NO4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2,5-pyridinedicarboxylic acid

References

1. Parkins A, et al. Structure. 2023 Mar 2;31(3):355-367.e4.

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