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Chemical Structure : MIF2 inhibitor 5d
Catalog No.: PC-20214Not For Human Use, Lab Use Only.
MIF2 inhibitor 5d is a selective inhibitor of d-dopachrome tautomerase (d-DT or MIF2) with IC50 of 1.0 μM for MIF2 tautomerase activity and a high selectivity over MIF.
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MIF2 inhibitor 5d is a selective inhibitor of d-dopachrome tautomerase (d-DT or MIF2) with IC50 of 1.0 μM for MIF2 tautomerase activity and a high selectivity over MIF.
MIF2 inhibitor 5d suppresses the proliferation of non-small cell lung cancer cells in two-dimensional (2D) and three-dimensional (3D) cell cultures, by the induction of cell cycle arrest via deactivation of the mitogen-activated protein kinase (MAPK) pathway
| M.Wt | 480.51 | |
| Formula | C26H19F3N2O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Zhangping Xiao, et al. J Med Chem. 2022 Feb 10;65(3):2059-2077.
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