Catalog No.: PC-61673Not For Human Use, Lab Use Only.
SBI-477 is a chemical probe that coordinately inhibits triacylglyceride (TAG) synthesis and enhances basal glucose uptake in human skeletal myocytes with EC50 of 100 nM and 1 uM, respectively.
SBI-477 is a chemical probe that coordinately inhibits triacylglyceride (TAG) synthesis and enhances basal glucose uptake in human skeletal myocytes with EC50 of 100 nM and 1 uM, respectively.
SBI-477 reduces expression of TXNIP and ARRDC4, negative regulators of insulin signaling, via deactivation of the transcription factor MondoA.
