Catalog No.: PC-61677Not For Human Use, Lab Use Only.
ATN-224 (Choline tetrathiomolybdate, WTX-101) is a specific, high-affinity copper binder that inhibits CuZn superoxide dismutase 1 (SOD1) with IC50 of 0.33 uM against purified bovine SOD1, leading to antiangiogenic and antitumour effects.
ATN-224 (Choline tetrathiomolybdate, WTX-101) is a specific, high-affinity copper binder that inhibits CuZn superoxide dismutase 1 (SOD1) with IC50 of 0.33 uM against purified bovine SOD1, leading to antiangiogenic and antitumour effects.
ATN-224 shows no binding to calcium, iron, magnesium, zinc, or manganese ions at 1 mM.
ATN-224 inhibits HUVEC proliferation with IC50 1.4 uM.
ATN-224 shows a potential therapy against Wilson's disease.
