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Chemical Structure : DS96432529
Catalog No.: PC-72664Not For Human Use, Lab Use Only.
DS96432529 (DS 96432529) is a potent and orally active bone anabolic agent with EC200 value of 0.024 ug/mL.
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DS96432529 (DS 96432529) is a potent and orally active bone anabolic agent with EC200 value of 0.024 ug/mL.
DS96432529 exhibited the best PK profile and high in vitro activity, showed the highest in vivo efficacy, showed significant synergistic effects when combined with alendronate or parathyroid hormone.
The mechanism of action is most likely mediated through CDK8 inhibition.
| M.Wt | 378.491 | |
| Formula | C18H26N4O3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Keiji Saito, et al. Bioorg Med Chem Lett. 2021 Dec 15;54:128440.
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