UNC10245131 | CIB1 inhibitor | Probechem Biochemicals

Chemical Structure : UNC10245131

UNC10245131 (UNC 10245131)

Catalog No.: PC-72667Not For Human Use, Lab Use Only.

UNC10245131 (UNC 10245131) is a potent, selective cyclic peptide inhibitor of calcium and integrin binding protein 1 (CIB1) with ITC Kd of 6.17 nM.

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Biological Activity

UNC10245131 (UNC 10245131) is a potent, selective cyclic peptide inhibitor of calcium and integrin binding protein 1 (CIB1) with ITC Kd of 6.17 nM.
UNC10245131 displays high selectivity over other EF-hand domain proteins.
UNC10245131 shows improved permeability and stability over previously identified linear peptide inhibitor UNC10245092.

Physicochemical Properties

M.Wt	1552.7406
Formula	C77H102N17O16S+
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	S-Ac-YKQPYWLINWC-NH2

References

1. Victoria A Haberman, et al. ACS Med Chem Lett. 2021 Oct 27;12(11):1832-1839.

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UNC10245131 (UNC 10245131)

Biological Activity

Physicochemical Properties

References

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