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UNC10245131

Chemical Structure : UNC10245131

CAS No.:

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UNC10245131 (UNC 10245131)

Catalog No.: PC-72667Not For Human Use, Lab Use Only.

UNC10245131 (UNC 10245131) is a potent, selective cyclic peptide inhibitor of calcium and integrin binding protein 1 (CIB1) with ITC Kd of 6.17 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    UNC10245131 (UNC 10245131) is a potent, selective cyclic peptide inhibitor of calcium and integrin binding protein 1 (CIB1) with ITC Kd of 6.17 nM.
    UNC10245131 displays high selectivity over other EF-hand domain proteins.
    UNC10245131 shows improved permeability and stability over previously identified linear peptide inhibitor UNC10245092.

    Physicochemical Properties

    M.Wt 1552.7406
    Formula C77H102N17O16S+
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    S-Ac-YKQPYWLINWC-NH2

    References

    1. Victoria A Haberman, et al. ACS Med Chem Lett. 2021 Oct 27;12(11):1832-1839.

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