TH301 | CRY2 stabilizer | Probechem Biochemicals

Chemical Structure : TH301

TH301 (TH 301)

Catalog No.: PC-49459Not For Human Use, Lab Use Only.

TH301 (TH 301) is a isoform-selective small molecule stabilizer of Cryptochrome 2 (CRY2).

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Biological Activity

TH301 (TH 301) is a isoform-selective small molecule stabilizer of Cryptochrome 2 (CRY2).
TH301 showed selectivity over CRY1, and no or only minor effects on CKIδ, CKIα and CK2 activities in vitro.

Physicochemical Properties

M.Wt	485.983
Formula	C24H24ClN3O4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(4-chlorophenyl)-N-(2-(4-methoxyphenyl)-5,5-dioxido-2,6-dihydro-4H-thieno[3,4-c]pyrazol-3-yl)cyclopentane-1-carboxamide

References

1. Miller S, et al. Nat Chem Biol. 2020 Jun;16(6):676-685.

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TH301 (TH 301)

Biological Activity

Physicochemical Properties

References

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