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TH301

Chemical Structure : TH301

CAS No.: 450338-32-6

TH301 (TH 301)

Catalog No.: PC-49459Not For Human Use, Lab Use Only.

TH301 (TH 301) is a isoform-selective small molecule stabilizer of Cryptochrome 2 (CRY2).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    TH301 (TH 301) is a isoform-selective small molecule stabilizer of Cryptochrome 2 (CRY2).
    TH301 showed selectivity over CRY1, and no or only minor effects on CKIδ, CKIα and CK2 activities in vitro.

    Physicochemical Properties

    M.Wt 485.983
    Formula C24H24ClN3O4S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    1-(4-chlorophenyl)-N-(2-(4-methoxyphenyl)-5,5-dioxido-2,6-dihydro-4H-thieno[3,4-c]pyrazol-3-yl)cyclopentane-1-carboxamide

    References

    1. Miller S, et al. Nat Chem Biol. 2020 Jun;16(6):676-685.

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