Chemical Structure : NOX-6-18
CAS No.: 898211-21-7
Catalog No.: PC-21239Not For Human Use, Lab Use Only.
NOX-6-18 is a potent, selective GPR132 antagonist with IC50 of 17 nM.
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NOX-6-18 is a potent, selective GPR132 antagonist with IC50 of 17 nM.
NOX-6-18 modulates macrophage reprogramming within pancreatic islets, decreases weight gain and enhances glucose metabolism in mice fed a high-fat diet.
M.Wt | 359.40 | |
Formula | C18H17NO5S | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
3-methyl-5-(N-phenethylsulfamoyl)benzofuran-2-carboxylic acid |
1. Jia-Le Wang, et al. Nat Metab. 2023 Sep 28. doi: 10.1038/s42255-023-00899-4.
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