NOX-6-18 | GPR132 inhibitor | Probechem Biochemicals

Chemical Structure : NOX-6-18

CAS No.: 898211-21-7

NOX-6-18 (GPR132 antagonist NOX-6-18)

Catalog No.: PC-21239Not For Human Use, Lab Use Only.

NOX-6-18 is a potent, selective GPR132 antagonist with IC50 of 17 nM.

Packing	Price	Stock
5 mg	$358	In stock
10 mg	$528	In stock
25 mg	$788	In stock
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Biological Activity

NOX-6-18 is a potent, selective GPR132 antagonist with IC50 of 17 nM.
NOX-6-18 modulates macrophage reprogramming within pancreatic islets, decreases weight gain and enhances glucose metabolism in mice fed a high-fat diet.

Physicochemical Properties

M.Wt	359.40
Formula	C18H17NO5S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-methyl-5-(N-phenethylsulfamoyl)benzofuran-2-carboxylic acid

References

1. Jia-Le Wang, et al. Nat Metab. 2023 Sep 28. doi: 10.1038/s42255-023-00899-4.

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NOX-6-18 (GPR132 antagonist NOX-6-18)

Biological Activity

Physicochemical Properties

References

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