Chemical Structure : Fumonisin B1
Catalog No.: PC-61424Not For Human Use, Lab Use Only.
A mycotoxin produced from F. moniliforme, and an inhibitor of ceramide synthase (sphingosine N-acyltransferase/CerS).
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A mycotoxin produced from F. moniliforme, and an inhibitor of ceramide synthase (sphingosine N-acyltransferase/CerS); attenuates the response of P388D1 cells to PAF and LPS by inhibiting ceramide formation; blocks the apoptotic response of HaCaT cells to the antiproliferative drug hexadecylphosphocholine, through inhibition of ceramide production; alteres cell morphology and decreases in cell proliferation in Swiss 3T3 cells.
M.Wt | 721.8 | |
Formula | C34H59NO15 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Merrill AH Jr, et al. J Biol Chem. 1993 Dec 25;268(36):27299-306.
2. Balsinde J, et al. J Biol Chem. 1997 Aug 15;272(33):20373-7.
3. Meivar-Levy I, et al. J Biol Chem. 1999 Feb 19;274(8):4607-12.
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