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Enexasogaol

Chemical Structure : Enexasogaol

CAS No.: 23513-13-5

Enexasogaol (6-Shogaol)

Catalog No.: PC-61375Not For Human Use, Lab Use Only.

Enexasogaol (6-Shogaol) is a pungent agent isolated from Zingiber officinale Roscoe, has been known to have anti-tumor and anti-inflammatory effects.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    Enexasogaol (6-Shogaol) is a pungent agent isolated from Zingiber officinale Roscoe, has been known to have anti-tumor and anti-inflammatory effects.
    Enexasogaol attenuates LPS-induced inflammation in BV2 microglia cells by activating PPAR-γ.
    Enexasogaol inhibits TNF-alpha mediated downregulation of adiponectin expression via different mechanisms in 3T3-L1 adipocytes.
    Enexasogaol also induces apoptotic cell death of human hepatoma p53 mutant Mahlavu subline via an oxidative stress-mediated caspase-dependent mechanism.

    Physicochemical Properties

    M.Wt 276.376
    Formula C17H24O3
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (4E)-1-(4-hydroxy-3-methoxyphenyl)dec-4-en-3-one

    References

    1. Isa Y, et al. Biochem Biophys Res Commun. 2008 Aug 29;373(3):429-34.

    2. Pan MH, et al. Mol Nutr Food Res. 2008 May;52(5):527-37.

    3. Chen CY, et al. J Agric Food Chem. 2007 Feb 7;55(3):948-54.

    4. Han Q,et al. Oncotarget. 2017 Jun 27;8(26):42001-42006.

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