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OX03050

Chemical Structure : OX03050

CAS No.: 1357581-47-5

OX03050 (OX-03050, OX 03050)

Catalog No.: PC-60631Not For Human Use, Lab Use Only.

OX03050 is a potent, competitive squalene synthase inhibitor that upregulate the LDLR in mouse and human liver cell lines with EC50 of 26 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    OX03050 is a potent, competitive squalene synthase inhibitor that upregulate the LDLR in mouse and human liver cell lines with EC50 of 26 nM.
    OX03050 exhibits much-improved pharmacokinetic profile and shows in vivo efficacy compared with OX03771.

    Physicochemical Properties

    M.Wt 254.329
    Formula C17H18O2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (E)-3-(4-styrylphenoxy)propan-1-ol

    References

    1. Kerr AG, et al. J Pharmacol Exp Ther. 2017 Jun;361(3):417-428.

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