OX03050 | Squalene synthase inhibitor | Probechem Biochemicals

Chemical Structure : OX03050

OX03050 (OX-03050, OX 03050)

Catalog No.: PC-60631Not For Human Use, Lab Use Only.

OX03050 is a potent, competitive squalene synthase inhibitor that upregulate the LDLR in mouse and human liver cell lines with EC50 of 26 nM.

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Biological Activity

OX03050 is a potent, competitive squalene synthase inhibitor that upregulate the LDLR in mouse and human liver cell lines with EC50 of 26 nM.
OX03050 exhibits much-improved pharmacokinetic profile and shows in vivo efficacy compared with OX03771.

Physicochemical Properties

M.Wt	254.329
Formula	C17H18O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(E)-3-(4-styrylphenoxy)propan-1-ol

References

1. Kerr AG, et al. J Pharmacol Exp Ther. 2017 Jun;361(3):417-428.

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OX03050 (OX-03050, OX 03050)

Biological Activity

Physicochemical Properties

References

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