Chemical Structure : LQB-118
Catalog No.: PC-60560Not For Human Use, Lab Use Only.
LQB-118 is an orally active pterocarpanquinone that exhibits antitumoral and antileishmanial activity both in vitro and in vivo.
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LQB-118 is an orally active pterocarpanquinone that exhibits antitumoral and antileishmanial activity both in vitro and in vivo.
LQB-118 induces apoptosis in cells derived from chronic myeloid leukemia patients, exhibiting multifactorial drug resistance phenotype such as P-glycoprotein, MRP1 and p53 overexpression.
LQB-118 shows activity active against intracellular amastigotes of L. amazonensis with IC50 of 1.4 uM, inhibits parasite growth in L.amazonensis-infected BALB/c mice.
M.Wt | 304.3 | |
Formula | C19H12O4 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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4. Martino T, et al. Prostate. 2018 Feb;78(2):140-151.
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