YPC-22026 |CAS:1964457-41-7 Probechem Biochemicals

Chemical Structure : YPC-22026

YPC-22026 (YPC22026)

Catalog No.: PC-62589Not For Human Use, Lab Use Only.

YPC-22026, a metabolically stable derivative of YPC-21661, is a novel small molecule inhibitor of the transcription factor Zinc-finger protein 143 (ZNF143), inhibits the binding of ZNF143 to DNA.

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Biological Activity

YPC-22026, a metabolically stable derivative of YPC-21661, is a novel small molecule inhibitor of the transcription factor Zinc-finger protein 143 (ZNF143), inhibits the binding of ZNF143 to DNA.
YPC-22026 induces tumor regression accompanied by the suppression of ZNF143-regulated genes in a mouse xenograft model.

Physicochemical Properties

M.Wt	331.254
Formula	C16H8F3N3O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(pyridine-3-ylethynyl)-5-(2-(trifluoromethoxy)phenyl)-1,3,4-oxadiazole

References

1. Haibara H, et al. Cancer Sci. 2017 May;108(5):1042-1048.

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YPC-22026 (YPC22026)

Biological Activity

Physicochemical Properties

References

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