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Chemical Structure : YPC-21661
Catalog No.: PC-62590Not For Human Use, Lab Use Only.
YPC-21661 is a novel small molecule inhibitor of the transcription factor Zinc-finger protein 143 (ZNF143).
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YPC-21661 is a novel small molecule inhibitor of the transcription factor Zinc-finger protein 143 (ZNF143).
YPC-21661 inhibits ZNF143 promoter activity and down-regulates the expression of the ZNF143-regulated genes, RAD51, PLK1, and Survivin。
YPC-21661 shows cytotoxicity and induces apoptosis in the human colon cancer cell line, HCT116 and human prostate cancer cell line, PC-3.
| M.Wt | 331.169 | |
| Formula | C15H11BrN2O2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Haibara H, et al. Cancer Sci. 2017 May;108(5):1042-1048.
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