YPC-21661 |CAS:1964456-15-2 Probechem Biochemicals

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Chemical Structure : YPC-21661

YPC-21661 (YPC21661)

Catalog No.: PC-62590Not For Human Use, Lab Use Only.

YPC-21661 is a novel small molecule inhibitor of the transcription factor Zinc-finger protein 143 (ZNF143).

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Biological Activity

YPC-21661 is a novel small molecule inhibitor of the transcription factor Zinc-finger protein 143 (ZNF143).
YPC-21661 inhibits ZNF143 promoter activity and down-regulates the expression of the ZNF143-regulated genes, RAD51, PLK1, and Survivin。
YPC-21661 shows cytotoxicity and induces apoptosis in the human colon cancer cell line, HCT116 and human prostate cancer cell line, PC-3.

Physicochemical Properties

M.Wt	331.169
Formula	C15H11BrN2O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(5-bromo-2-methoxyphenyl)-3-(pyridine-3-yl) propiolamide

References

1. Haibara H, et al. Cancer Sci. 2017 May;108(5):1042-1048.

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YPC-21661 (YPC21661)

Biological Activity

Physicochemical Properties

References

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