Catalog No.: PC-62470Not For Human Use, Lab Use Only.
GGTI-2133 is a cell-permeable, non-thiol peptidomimetic that acts as a potent and selective inhibitor of GGTase I (IC50=38 nM), displays 40-fold selectivity over FTase.
GGTI-2133 is a cell-permeable, non-thiol peptidomimetic that acts as a potent and selective inhibitor of GGTase I (IC50=38 nM), displays 40-fold selectivity over FTase.
GGTI-2133 increases deformability and impairs low O2 tension-induced ATP release in healthy human erythrocytes.
GGTI-2133 inhibits antigen-induced BSM hyperresponsiveness, probably by reducing downstream signal transduction of RhoA.
