Chemical Structure : RP-54745
CAS No.: 135330-08-4
Catalog No.: PC-24063Not For Human Use, Lab Use Only.
RP-54745 is a potential antirheumatic compound and interleukin-1 (IL-1) inhibitor, inhibits LPS-induced IL-1 production by murine peritoneal macrophages.
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RP-54745 is a potential antirheumatic compound and interleukin-1 (IL-1) inhibitor, inhibits LPS-induced IL-1 production by murine peritoneal macrophages.
RP-54745 effectively repressed KSHV + PEL cell growth through inducing tumor cell apoptosis.
RP-54745 significantly reduced hyperinflammation in tumor microenvironment including myeloid cells and neutrophils infiltration, as well as blocking IL-1 signaling molecules expression in primary effusion lymphoma (PEL) xenograft model.
M.Wt | 297.82 | |
Formula | C13H12ClNOS2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
4-Chloro-5-(1-methyl-3,4-dihydroisoquinolin-2(1H)-yl)-3H-1,2-dithiol-3-one |
1. Folliard F, et al. Agents Actions. 1992 May;36(1-2):119-26.
2. Dai L, et al. J Med Virol. 2025 Feb;97(2):e70200.
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