Germinone | KAI2 agonist | Probechem Biochemicals

Chemical Structure : Germinone

Germinone (Germinone A)

Catalog No.: PC-24062Not For Human Use, Lab Use Only.

Germinone (Germinone A) is a small molecule agonist HTL/KAI2 (KAI2), also binds to DWARF14 (D14), shows germination-inducing activity for thermo-inhibited Arabidopsis seed.

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Biological Activity

Germinone (Germinone A) is a small molecule agonist HTL/KAI2 (KAI2), also binds to DWARF14 (D14), shows germination-inducing activity for thermo-inhibited Arabidopsis seed.
Germinone inhibited KAI2-dependent dMYLG hydrolysis with IC50 of 0.58 uM.
Germinone strongly inhibited YLG hydrolysis by D14 with IC50 of 0.01 uM.

Physicochemical Properties

M.Wt	311.29
Formula	C17H13NO5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-methyl-5-((3-nitro-[1,1'-biphenyl]-4-yl)oxy)furan-2(5H)-one

References

1. Okabe S, et al. Biochem Biophys Res Commun. 2023 Mar 15;649:110-117.

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Germinone (Germinone A)

Biological Activity

Physicochemical Properties

References

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