Chemical Structure : SOFTI
CAS No.: 1200133-34-1
Catalog No.: PC-21054Not For Human Use, Lab Use Only.
SOFTI is a small molecule inhibitor of O-fucosyltransferase SPINDLY (SPY) with IC50 of 13.32 uM, binds to the GDP-fucose-binding pocket of SPY and competitively inhibits GDP-fucose binding.
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M.Wt | 497.74 | |
Formula | C26H36KNO4S | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
5-(cyclohex-1-en-1-yl)-3-((1r,4R)-N-((1r,4R)-4-methoxycyclohexyl)-4-methylcyclohexane-1-carboxamido)thiophene-2-carboxylic acid |
1. Aizezi Y, et al. Plant Cell. 2023 Dec 20:koad299.
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