Chemical Structure : BDP-13176
CAS No.: 2290660-61-4
Catalog No.: PC-21071Not For Human Use, Lab Use Only.
BDP-13176 is a small molecule inhibitor of actin-bundling protein Fascin-1 (Fscn1) with SPR and ITC Kd values of 85 and 50 nM, respectively, inhibits fascin-mediated actin bundling with IC50 of 240 nM.
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BDP-13176 is a small molecule inhibitor of actin-bundling protein Fascin-1 (Fscn1) with SPR and ITC Kd values of 85 and 50 nM, respectively, inhibits fascin-mediated actin bundling with IC50 of 240 nM.
BDP-13176 is a useful chemical probe for fascin's potential role in tumor invasion and metastasis.
M.Wt | 497.38 | |
Formula | C24H22Cl2N6O2 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
1H-Pyrazolo[4,3-c]pyridine-7-carboxamide, 5-[(3,4-dichlorophenyl)methyl]-4,5-dihydro-4-oxo-1-(4-piperidinyl)-N-4-pyridinyl- |
1. Stuart Francis, et al. Bioorg Med Chem Lett. 2019 Apr 15;29(8):1023-1029.
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