Chemical Structure : SIBA
CAS No.: 35899-54-8
Catalog No.: PC-45525Not For Human Use, Lab Use Only.
SIBA (5'-Isobutylthioadenosine) is an inhibitor of the IMP-selective cytosolic 5'-nucleotidase (IC50=2-6 mM), also inhibits the ecto-5'-nucleotidase of polymorphonuclear leucocytes.
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SIBA (5'-Isobutylthioadenosine) is an inhibitor of the IMP-selective cytosolic 5'-nucleotidase (IC50=2-6 mM), also inhibits the ecto-5'-nucleotidase of polymorphonuclear leucocytes.
M.Wt | 339.4132 | |
Formula | C14H21N5O3S | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
Adenosine, 5'-S-(2-methylpropyl)-5'-thio- |
1. Meghji P, et al. Biochem J. 1993 May 1;291 ( Pt 3):833-9.
2. Skladanowski AC, et al. Biochem J. 1989 Aug 15;262(1):203-8.
3. Lawrence F, et al. Biochem J. 1982 Jun 15;204(3):853-9.
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