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SIBA

Chemical Structure : SIBA

CAS No.: 35899-54-8

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SIBA (5'-Isobutylthioadenosine)

Catalog No.: PC-45525Not For Human Use, Lab Use Only.

SIBA (5'-Isobutylthioadenosine) is an inhibitor of the IMP-selective cytosolic 5'-nucleotidase (IC50=2-6 mM), also inhibits the ecto-5'-nucleotidase of polymorphonuclear leucocytes.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

SIBA (5'-Isobutylthioadenosine) is an inhibitor of the IMP-selective cytosolic 5'-nucleotidase (IC50=2-6 mM), also inhibits the ecto-5'-nucleotidase of polymorphonuclear leucocytes.

Physicochemical Properties

M.Wt 339.4132
Formula C14H21N5O3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Adenosine, 5'-S-(2-methylpropyl)-5'-thio-

References

1. Meghji P, et al. Biochem J. 1993 May 1;291 ( Pt 3):833-9.

2. Skladanowski AC, et al. Biochem J. 1989 Aug 15;262(1):203-8.

3. Lawrence F, et al. Biochem J. 1982 Jun 15;204(3):853-9.

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