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Deferasirox

Chemical Structure : Deferasirox

CAS No.: 201530-41-8

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Deferasirox (ICL670, ICL-670)

Catalog No.: PC-45179Not For Human Use, Lab Use Only.

Deferasirox (ICL670) is an oral iron chelator that used to reduce chronic iron overload, also induces apoptosis in myeloid leukemia cells by targeting caspase.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Deferasirox (ICL670) is an oral iron chelator that used to reduce chronic iron overload, also induces apoptosis in myeloid leukemia cells by targeting caspase.

Physicochemical Properties

M.Wt 373.3615
Formula C21H15N3O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Benzoic acid, 4-[3,5-bis(2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]-

References

1. Sobbe A, et al. J Gastroenterol Hepatol. 2015 Mar;30(3):638-45.

2. Kim JL, et al. Acta Haematol. 2011;126(4):241-5.

3. Lee DH, et al. Exp Hematol. 2013 Jun;41(6):539-46.

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