Chemical Structure : Emixustat hydrochloride
CAS No.:
1141934-97-5
Emixustat hydrochloride
(ACU-4429 hydrochloride)
Catalog No. : PC-45685Not For Human Use, Lab Use Only.
Emixustat (ACU-4429) hydrochloride is a first in class small-molecule inhibitor of the visual cycle isomerase (RPE65) with IC50 of 4.4 nM.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-4568501
Biological Activity
Emixustat (ACU-4429) hydrochloride is a first in class small-molecule inhibitor of the visual cycle isomerase (RPE65 ) with IC50 of 4.4 nM.
Physicochemical Properties
M.Wt
299.8362
Formula
C16H26ClNO2
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
DMSO: ≥ 44 mg/mL
Chemical Name/SMILES
Benzenemethanol, α-(2-aminoethyl)-3-(cyclohexylmethoxy)-, hydrochloride (1:1), (αR)-
References
1. Kiser PD, et al. Nat Chem Biol.
2. Bavik C, et al. PLoS One.
3. Zhang J, et al. J Clin Invest.
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