BACH2 inhibitor compound 8

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Chemical Structure : BACH2 inhibitor compound 8

CAS No.: 1325718-66-8

Catalog No.: PC-72817Not For Human Use, Lab Use Only.

BACH2 inhibitor compound 8 is a potent, dual BACH2/BACH1 inhibitor.

Packing	Price	Stock
2 mg	$298	In stock
5 mg	$498	In stock
10 mg	$758	In stock
25 mg		Get quote
100 mg		Get quote

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

BACH2 inhibitor compound 8 is a potent, dual BACH2/BACH1 inhibitor.
BACH inhibitor compound 8 lowered glycemia and increased plasma insulin levels in diabetic mice, and restored insulin secretion in diabetic mice and human islets.

Physicochemical Properties

M.Wt	465.451
Formula	C20H18F3N5O3S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1-Methyl-2-(6-trifluoromethoxy-benzothiazol-2-ylamino)-1H-benzoimidazole-5-carboxylic acid (2-methoxy-ethyl)-amide

References

1. Jinsook Son, et al. J Clin Invest. 2021 Dec 15;131(24):e153876.

2. Patent WO2012094580

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